Necessity for craniospinal irradiation of germinoma with positive cytology without spinal lesion on MR imaging-A controversy

Necessity for craniospinal irradiation of germinoma with positive cytology without spinal lesion on MR imaging-A controversy

 Cerebrospinal fluid (CSF) cytology and spinal MR imaging are routinely carried out for staging earlier than therapy of intracranial germinoma. Nonetheless, the interpretation of the outcomes of CSF cytology poses 2 unresolved scientific questions: (1) Does constructive CSF cytology correlate with the presence of spinal lesion earlier than therapy? and (2) Is craniospinal irradiation (CSI) […]