S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma.

S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma.

Uterine carcinosarcoma (UCS) represents a real instance of most cancers related to epithelial-mesenchymal transition (EMT), which displays most cancers stem cell (CSC)-like traits. Though S100A4 is an inducer of EMT, little is understood about its involvement in UCS tumorigenesis. Herein, we targeted on the useful function of S100A4 throughout growth of UCS. Expression of S100A4 and molecules related to its operate […]