Vimseltinib: A precision CSF1R therapy for tenosynovial giant cell tumors and diseases promoted by macrophages

Vimseltinib: A precision CSF1R therapy for tenosynovial giant cell tumors and diseases promoted by macrophages

Macrophages will be co-opted to contribute to neoplastic, neurologic, and inflammatory ailments. Colony stimulating issue 1 receptor (CSF1R)-dependent macrophages and different inflammatory cells can suppress the adaptive immune system in most cancers and contribute to angiogenesis, tumor progress, and metastasis. CSF1R-expressing osteoclasts mediate bone degradation in osteolytic cancers and cancers that metastasize to bone. Within the […]