Development of histidine-tagged cyclic peptide functionalized monolithic material for the affinity purification of antibodies in biological matrices

Development of histidine-tagged cyclic peptide functionalized monolithic material for the affinity purification of antibodies in biological matrices

The quickly growing purposes of monoclonal antibodies (mAbs) in remedy have necessitated the event of mAb manufacturing and purification applied sciences for each educational and industrial utilization. Herein, a histidine-tagged cyclic peptide  functionalized monolithic materials was developed by the metallic ion chelation-based method. The ensuing materials possessed appropriate affinity and peptide ligand density (13.Eight mg […]