array – Page 4 – Citología y Biografía de Los biólogos españoles

Generation of an induced pluripotent stem cell line from a Bartter syndrome patient with the homozygote mutation p.A244D (c.731C>A) in SLC12A1 geneGeneration of an induced pluripotent stem cell line from a Bartter syndrome patient with the homozygote mutation p.A244D (c.731C>A) in SLC12A1 gene

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Bartter Syndrome (BS) is a gaggle of uncommon inherited autosome-recessive illness, which might be attributable to the gene mutations of sodium-potassium-chloride cotransporter gene (SLC12A1). Right here, the urine cells (UCs)

PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis.PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis.

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Metformin has been broadly used to alleviate hyperglycemia in sufferers with kind 2 diabetes primarily through suppressing hepatic gluconeogenesis. Nevertheless, the underlying mechanism stays incompletely clear. Right here, we aimed

Type II-Metacaspases are involved in cell stress but not in cell death in the unicellular green alga Dunaliella tertiolecta.Type II-Metacaspases are involved in cell stress but not in cell death in the unicellular green alga Dunaliella tertiolecta.

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Ultraviolet radiation (UVR; 280-400 nm) has an awesome impression on aquatic ecosystems by affecting ecophysiological and biogeochemical processes as a consequence of the worldwide change situation generated by anthropogenic actions.

Cell-Free DNA Analysis by Whole-Exome Sequencing for Hepatocellular Carcinoma: A Pilot Study in ThailandCell-Free DNA Analysis by Whole-Exome Sequencing for Hepatocellular Carcinoma: A Pilot Study in Thailand

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Cell-free DNA (cfDNA) has been used as a non-invasive biomarker for detecting cancer-specific mutations. Nevertheless, the mutational profile of cfDNA in Thai sufferers with hepatocellular carcinoma (HCC) has not been

S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma.S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma.

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Uterine carcinosarcoma (UCS) represents a real instance of most cancers related to epithelial-mesenchymal transition (EMT), which displays most cancers stem cell (CSC)-like traits. Though S100A4 is an inducer of EMT, little is

Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging.Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging.

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Antibody (Ab) fragments have nice medical potential as most cancers therapeutics and diagnostics. Their small measurement permits for quick clearance from blood, low immunoreactivity, higher tumor penetration, and less complicated

Vimseltinib: A precision CSF1R therapy for tenosynovial giant cell tumors and diseases promoted by macrophagesVimseltinib: A precision CSF1R therapy for tenosynovial giant cell tumors and diseases promoted by macrophages

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Macrophages will be co-opted to contribute to neoplastic, neurologic, and inflammatory ailments. Colony stimulating issue 1 receptor (CSF1R)-dependent macrophages and different inflammatory cells can suppress the adaptive immune system in

Anti-CXCR4 Single-Chain Variable Fragment Antibodies Have Anti-Tumor ActivityAnti-CXCR4 Single-Chain Variable Fragment Antibodies Have Anti-Tumor Activity

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Monoclonal antibodies (mAbs) are massive and have limitations as most cancers therapeutics. Human single-chain variable fragment (scFv) is a small antibody as various. It may simply enter most cancers tissues,

New monoclonal antibodies that recognize an unglycosylated, conserved, extracellular region of CD44 in vitro and in vivo, and can block tumorigenesisNew monoclonal antibodies that recognize an unglycosylated, conserved, extracellular region of CD44 in vitro and in vivo, and can block tumorigenesis

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CD44 is a transmembrane glycoprotein that binds to hyaluronic acid, performs roles in various mobile processes and is expressed in quite a lot of cell sorts. It’s up-regulated in stem

Clinical effect of rabbit anti-thymocyte globulin for chronic active antibody-mediated rejection after kidney transplantationClinical effect of rabbit anti-thymocyte globulin for chronic active antibody-mediated rejection after kidney transplantation

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Continual energetic antibody-mediated rejection (CAAMR) is a frequent reason behind late graft loss. Nonetheless, efficient remedy for CAAMR after kidney transplantation has not but been established. Right here, we current